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Conditional knockout of polarity complex (atypical) PKCι reveals an anti-inflammatory function mediated by NF-κB
The conserved proteins of the polarity complex made up of atypical PKC (aPKC, isoforms ι and ζ), Par6, and Par3 determine asymmetry in several cell types, from Caenorhabditis elegans oocytes to vertebrate epithelia and neurons. We previously showed that aPKC is down-regulated in intestinal epithelia...
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| 發表在: | Mol Biol Cell |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The American Society for Cell Biology
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4945138/ https://ncbi.nlm.nih.gov/pubmed/27226486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-02-0086 |
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