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The BAG-1 isoform BAG-1M regulates keratin-associated Hsp70 chaperoning of aPKC in intestinal cells during activation of inflammatory signaling

Atypical PKC (ι/λ and ζ; hereafter referred to as aPKC) is a key player in the acquisition of epithelial polarity and participates in other signaling cascades including the control of NF-κB signaling. This kinase is post-translationally regulated through Hsp70-mediated refolding. Previous work has s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mashukova, Anastasia, Kozhekbaeva, Zhanna, Forteza, Radia, Dulam, Vipin, Figueroa, Yolanda, Warren, Robert, Salas, Pedro J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132394/
https://ncbi.nlm.nih.gov/pubmed/24876225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.151084
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