Tau Pathology is Present In Vivo and Develops In Vitro in Sensory Neurons from Human P301S Tau Transgenic Mice: A System for Screening Drugs against Tauopathies

Intracellular tau aggregates are the neuropathological hallmark of several neurodegenerative diseases, including Alzheimer's disease, progressive supranuclear palsy, and cases of frontotemporal dementia, but the link between these aggregates and neurodegeneration remains unclear. Neuronal model...

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Main Authors: Mellone, Manuela, Kestoras, Dimitra, Andrews, Melissa R., Dassie, Elisa, Crowther, R. Anthony, Stokin, Gorazd B., Tinsley, Jon, Horne, Graeme, Goedert, Michel, Tolkovsky, Aviva M., Spillantini, Maria Grazia
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828468/
https://ncbi.nlm.nih.gov/pubmed/24227726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4933-12.2013
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