Analysis of Tau Phosphorylation and Truncation in a Mouse Model of Human Tauopathy

Recent evidence has suggested that truncation of tau protein at the caspase cleavage site D421 precedes hyperphosphorylation and may be necessary for the assembly of tau into filaments in Alzheimer’s disease and other tauopathies. Here we have investigated the time course of the appearance of phosph...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Delobel, Patrice, Lavenir, Isabelle, Fraser, Graham, Ingram, Esther, Holzer, Max, Ghetti, Bernardino, Spillantini, Maria Grazia, Crowther, R. Anthony, Goedert, Michel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2008
Pynciau:
Regular Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189621/
https://ncbi.nlm.nih.gov/pubmed/18079436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070627
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