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Analysis of Tau Phosphorylation and Truncation in a Mouse Model of Human Tauopathy
Recent evidence has suggested that truncation of tau protein at the caspase cleavage site D421 precedes hyperphosphorylation and may be necessary for the assembly of tau into filaments in Alzheimer’s disease and other tauopathies. Here we have investigated the time course of the appearance of phosph...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Investigative Pathology
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2189621/ https://ncbi.nlm.nih.gov/pubmed/18079436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070627 |
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