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Structural Features of the Regulatory ACT Domain of Phenylalanine Hydroxylase
Phenylalanine hydroxylase (PAH) catalyzes the conversion of L-Phe to L-Tyr. Defects in PAH activity, caused by mutations in the human gene, result in the autosomal recessively inherited disease hyperphenylalaninemia. PAH activity is regulated by multiple factors, including phosphorylation and ligand...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3828330/ https://ncbi.nlm.nih.gov/pubmed/24244510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079482 |
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