Triptolide Induces Growth Inhibition and Apoptosis of Human Laryngocarcinoma Cells by Enhancing p53 Activities and Suppressing E6-Mediated p53 Degradation

Triptolide, an active compound extracted from Chinese herb Leigongteng (Tripterygium wilfordii Hook F.), shows a broad-spectrum of anticancer activity through its cytotoxicity. However, the efficacy of triptolide on laryngocarcinoma rarely been evaluated, and the mechanism by which triptolide-induce...

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Detalhes bibliográficos
Main Authors: Zhao, Fei, Huang, Weiwei, Ousman, Tamgue, Zhang, Bin, Han, Yangyang, Clotaire, Daguia Zambe John, Wang, Chen, Chang, Huanhuan, Luo, Huanan, Ren, Xiaoyong, Lei, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828261/
https://ncbi.nlm.nih.gov/pubmed/24244715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080784
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