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Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation
BACKGROUND: Triptolide is a medicinal herb-derived diterpene triepoxide with potent anti-tumor activity, mainly, correlated with its ability to inhibit and inactivate subunits of RNA polymerase II, thereby suppressing global gene transcription. Epigenetic imbalance including histone methylation are...
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| Publicado no: | Asian Pac J Cancer Prev |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
West Asia Organization for Cancer Prevention
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5720660/ https://ncbi.nlm.nih.gov/pubmed/28952292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22034/APJCP.2017.18.9.2519 |
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