Senescence‐associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15

The risk of colorectal cancer (CRC) varies between people, and the cellular mechanisms mediating the differences in risk are largely unknown. Senescence has been implicated as a causative cellular mechanism for many diseases, including cancer, and may affect the risk for CRC. Senescent fibroblasts t...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Guo, Yuna, Ayers, Jessica L., Carter, Kelly T., Wang, Ting, Maden, Sean K., Edmond, Darwin, Newcomb P, Polly, Li, Christopher, Ulrich, Cornelia, Yu, Ming, Grady, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6826139/
https://ncbi.nlm.nih.gov/pubmed/31389184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13013
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