Radiation-Induced Senescence Reprograms Secretory and Metabolic Pathways in Colon Cancer HCT-116 Cells

Understanding the global metabolic changes during the senescence of tumor cells can have implications for developing effective anti-cancer treatment strategies. Ionizing radiation (IR) was used to induce senescence in a human colon cancer cell line HCT-116 to examine secretome and metabolome profile...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Nagineni, Chandrasekharam N., Naz, Sarwat, Choudhuri, Rajani, Chandramouli, Gadisetti V. R., Krishna, Murali C., Brender, Jeffrey R., Cook, John A., Mitchell, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8124941/
https://ncbi.nlm.nih.gov/pubmed/34063570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094835
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