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Entrainment of superoxide rhythm by menadione in HCT116 colon cancer cells

Reactive oxygen species (ROS) are primary effectors of cytotoxicity induced by many anti-cancer drugs. Rhythms in the pseudo-steady-state (PSS) levels of particular intracellular ROS in cancer cells and their relevance to drug effectiveness are unknown thus far. We report that the PSS levels of intr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kizhuveetil, Uma, Palukuri, Meghana V., Sharma, Priyanshu, Karunagaran, Devarajan, Rengaswamy, Raghunathan, Suraishkumar, G. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399287/
https://ncbi.nlm.nih.gov/pubmed/30833672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40017-7
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