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Enantioselective Syntheses of FR901464 and Spliceostatin A: Potent Inhibitors of Spliceosome
[Image: see text] Enantioselective syntheses of FR901464 and Spliceostatin A, potent spliceosome inhibitors are described. The synthesis of FR901464 has been accomplished in a convergent manner in 10 linear steps (20 total steps). The synthesis of the A-tetrahydropyran ring was constructed from (R)-...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3827971/ https://ncbi.nlm.nih.gov/pubmed/24050251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol4024634 |
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