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Acceleration of Tuberculosis Treatment by Adjunctive Therapy with Verapamil as an Efflux Inhibitor

Rationale: A major priority in tuberculosis (TB) is to reduce effective treatment times and emergence of resistance. Recent studies in macrophages and zebrafish show that inhibition of mycobacterial efflux pumps with verapamil reduces the bacterial drug tolerance and may enhance drug efficacy. Objec...

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Detalhes bibliográficos
Main Authors: Gupta, Shashank, Tyagi, Sandeep, Almeida, Deepak V., Maiga, Mariama C., Ammerman, Nicole C., Bishai, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827702/
https://ncbi.nlm.nih.gov/pubmed/23805786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201304-0650OC
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