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Adjuvant Host-Directed Therapy with Types 3 and 5 but Not Type 4 Phosphodiesterase Inhibitors Shortens the Duration of Tuberculosis Treatment

Background. Shortening tuberculosis treatment could significantly improve patient adherence and decrease the development of drug resistance. Phosphodiesterase inhibitors (PDE-Is) have been shown to be beneficial in animal models of tuberculosis. We assessed the impact of PDE-Is on the duration of tr...

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Detalhes bibliográficos
Main Authors: Maiga, Mamoudou, Ammerman, Nicole C., Maiga, Mariama C., Tounkara, Anatole, Siddiqui, Sophia, Polis, Michael, Murphy, Robert, Bishai, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699007/
https://ncbi.nlm.nih.gov/pubmed/23641020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit187
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