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Successful Shortening of Tuberculosis Treatment Using Adjuvant Host-Directed Therapy with FDA-Approved Phosphodiesterase Inhibitors in the Mouse Model

Global control of tuberculosis (TB), an infectious disease that claims nearly 2 million lives annually, is hindered by the long duration of chemotherapy required for curative treatment. Lack of adherence to this intense treatment regimen leads to poor patient outcomes, development of new or addition...

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Bibliografiske detaljer
Main Authors: Maiga, Mamoudou, Agarwal, Nisheeth, Ammerman, Nicole C., Gupta, Radhika, Guo, Haidan, Maiga, Marama C., Lun, Shichun, Bishai, William R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272040/
https://ncbi.nlm.nih.gov/pubmed/22319585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030749
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