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Characterization of the role of EGF-A of low density lipoprotein receptor in PCSK9 binding

Proprotein convertase subtilisin kexin-like 9 (PCSK9) promotes the degradation of low density lipoprotein receptor (LDLR) and plays an important role in regulating plasma LDL-cholesterol levels. We have shown that the epidermal growth factor precursor homology domain A (EGF-A) of the LDLR is critica...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Gu, Hong-mei, Adijiang, Ayinuer, Mah, Matthew, Zhang, Da-wei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Biochemistry and Molecular Biology 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826682/
https://ncbi.nlm.nih.gov/pubmed/24103783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M041129
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