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Characterization of the role of EGF-A of low density lipoprotein receptor in PCSK9 binding
Proprotein convertase subtilisin kexin-like 9 (PCSK9) promotes the degradation of low density lipoprotein receptor (LDLR) and plays an important role in regulating plasma LDL-cholesterol levels. We have shown that the epidermal growth factor precursor homology domain A (EGF-A) of the LDLR is critica...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3826682/ https://ncbi.nlm.nih.gov/pubmed/24103783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M041129 |
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