Role of the hydrophobic and charged residues in the 218–226 region of apoA-I in the biogenesis of HDL(1)

We investigated the significance of hydrophobic and charged residues 218–226 on the structure and functions of apoA-I and their contribution to the biogenesis of HDL. Adenovirus-mediated gene transfer of apoA-I[L218A/L219A/V221A/L222A] in apoA-I(−/−) mice decreased plasma cholesterol and apoA-I leve...

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Detalhes bibliográficos
Main Authors: Fotakis, Panagiotis, Kateifides, Andreas K., Gkolfinopoulou, Christina, Georgiadou, Dimitra, Beck, Melissa, Gründler, Katharina, Chroni, Angeliki, Stratikos, Efstratios, Kardassis, Dimitris, Zannis, Vassilis I.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826676/
https://ncbi.nlm.nih.gov/pubmed/23990662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M038356
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