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Significance of the hydrophobic residues 225–230 of apoA-I for the biogenesis of HDL(1)

We studied the significance of four hydrophobic residues within the 225–230 region of apoA-I on its structure and functions and their contribution to the biogenesis of HDL. Adenovirus-mediated gene transfer of an apoA-I[F225A/V227A/F229A/L230A] mutant in apoA-I(−/−) mice decreased plasma cholesterol...

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Bibliografiske detaljer
Main Authors: Fotakis, Panagiotis, Tiniakou, Ioanna, Kateifides, Andreas K., Gkolfinopoulou, Christina, Chroni, Angeliki, Stratikos, Efstratios, Zannis, Vassilis I., Kardassis, Dimitris
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826677/
https://ncbi.nlm.nih.gov/pubmed/24123812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M043489
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