Caveolin-1 is a negative regulator of MMP-1 gene expression in human dermal fibroblasts via inhibition of Erk1/2/Ets1 signaling pathway

BACKGROUND: Caveolar raft domains, also termed caveolae, are flask shaped invaginations that require the expression of the structural protein caveolin-1 (cav-1). Matrix metalloproteinase 1 (MMP-1) is a collagenase capable of degrading insoluble triple helical collagens. Deregulation of MMP-1 contrib...

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Detaylı Bibliyografya
Asıl Yazarlar: Haines, Paul, Samuel, Glady H., Cohen, Heather, Trojanowska, Maria, Bujor, Andreea M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826600/
https://ncbi.nlm.nih.gov/pubmed/21925842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdermsci.2011.08.005
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