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Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells
Pancreatic islet β-cell insufficiency underlies pathogenesis of diabetes mellitus; thus, functional β-cell replacement from renewable sources is the focus of intensive worldwide effort. However, in vitro production of progeny that secrete insulin in response to physiological cues from primary human...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3826580/ https://ncbi.nlm.nih.gov/pubmed/24252877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00940 |
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