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Neonatal β Cell Development in Mice and Humans Is Regulated by Calcineurin/NFAT
Little is known about the mechanisms governing neonatal growth and maturation of organs. Here we demonstrate that calcineurin/Nuclear Factor of Activated T cells (Cn/NFAT) signaling regulates neonatal pancreatic development in mouse and human islets. Inactivation of calcineurin b1 (Cnb1) in mouse is...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587727/ https://ncbi.nlm.nih.gov/pubmed/22814600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.05.014 |
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