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Neonatal β Cell Development in Mice and Humans Is Regulated by Calcineurin/NFAT

Little is known about the mechanisms governing neonatal growth and maturation of organs. Here we demonstrate that calcineurin/Nuclear Factor of Activated T cells (Cn/NFAT) signaling regulates neonatal pancreatic development in mouse and human islets. Inactivation of calcineurin b1 (Cnb1) in mouse is...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Goodyer, William R., Gu, Xueying, Liu, Yinghua, Bottino, Rita, Crabtree, Gerald R., Kim, Seung K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587727/
https://ncbi.nlm.nih.gov/pubmed/22814600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.05.014
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