Calcineurin/NFAT Signaling Is Required for Neuregulin-Regulated Schwann Cell Differentiation

Schwann cells develop from multipotent neural crest cells and form myelin sheaths around axons that allow rapid transmission of action potentials. Neuregulin signaling through the ErbB receptor regulates Schwann cell development; however, the downstream pathways are not fully defined. We find that m...

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Главные авторы: Kao, Shih-Chu, Wu, Hai, Xie, Jianming, Chang, Ching-Pin, Ranish, Jeffrey A., Graef, Isabella A., Crabtree, Gerald R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790385/
https://ncbi.nlm.nih.gov/pubmed/19179536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1166562
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