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Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery

Congenital obstructive nephropathy is the principal cause of renal failure in infants and children. The underlying molecular and cellular mechanisms of this disease, however, remain largely undetermined. We generated a mouse model of congenital obstructive nephropathy that resembles ureteropelvic ju...

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Detalhes bibliográficos
Main Authors: Chang, Ching-Pin, McDill, Bradley W., Neilson, Joel R., Joist, Heidi E., Epstein, Jonathan A., Crabtree, Gerald R., Chen, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC379320/
https://ncbi.nlm.nih.gov/pubmed/15057312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420049
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