Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery

Congenital obstructive nephropathy is the principal cause of renal failure in infants and children. The underlying molecular and cellular mechanisms of this disease, however, remain largely undetermined. We generated a mouse model of congenital obstructive nephropathy that resembles ureteropelvic ju...

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Bibliographic Details
Main Authors: Chang, Ching-Pin, McDill, Bradley W., Neilson, Joel R., Joist, Heidi E., Epstein, Jonathan A., Crabtree, Gerald R., Chen, Feng
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2004
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC379320/
https://ncbi.nlm.nih.gov/pubmed/15057312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420049
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