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Highly Z-Selective and Enantioselective Ring Opening/Cross Metathesis Catalyzed by Resolved Stereogenic-At-Ru Complex

The synthesis of a ruthenium complex that catalyzes Z-selective (up to 98% Z) asymmetric ring opening/cross metathesis with high enantioselectivity (up to 95% ee) is reported. Synthesis of the catalyst features the resolution of a chelating NHC alkylidene complex by ligand substitution with a chiral...

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Detalhes bibliográficos
Main Authors: Hartung, John, Grubbs, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826570/
https://ncbi.nlm.nih.gov/pubmed/23822901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4046422
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