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Catalytic, Enantioselective Synthesis of 1,2-anti Diols via Asymmetric Ring Opening/Cross Metathesis

An enantioselective method for the synthesis of 1,2-anti diols has been developed. A cyclometallated chiral-at-Ru complex catalyzes the asymmetric ring opening/cross metathesis of di–oxygenated cyclobutenes, resulting in functionally rich synthetic building blocks. Syntheses of the insect pheromone...

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Detalhes bibliográficos
Main Authors: Hartung, John, Grubbs, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037230/
https://ncbi.nlm.nih.gov/pubmed/24554613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201310767
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