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Inflammasome-mediated secretion of IL-1β in human monocytes through TLR2 activation; Modulation by dietary fatty acids
Many studies have shown that TLR4 and TLR2 deficient mice are protected from high fat diet-induced inflammation and insulin resistance, suggesting that saturated fatty acids derived from the high fat diet activate TLR-mediated proinflammatory signaling pathways and induce insulin resistance. However...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3825708/ https://ncbi.nlm.nih.gov/pubmed/24043885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300298 |
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