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Cooperative Stabilization of Zn(2+):DNA Complexes Through Netropsin Binding in the Minor Groove of FdU-Substituted DNA
The simultaneous binding of netropsin in the minor groove and Zn(2+) in the major groove of a DNA hairpin that includes 10 consecutive FdU nucleotides at the 3′-terminus (3’FdU) was demonstrated based upon NMR spectroscopy, circular dichroism (CD), and computational modeling studies. The resulting Z...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3825453/ https://ncbi.nlm.nih.gov/pubmed/23153072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2012.732343 |
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