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Mutationally Activated PIK3CA(H1047R) Cooperates With BRAF(V600E) To Promote Lung Cancer Progression
Adenocarcinoma of the lung, a leading cause of cancer death, frequently displays mutational activation of the KRAS proto-oncogene but, unlike lung cancers expressing mutated EGFR, ROS1 or ALK, there is no pathway-targeted therapy for patients with KRAS mutated lung cancer. In pre-clinical models, ex...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3825323/ https://ncbi.nlm.nih.gov/pubmed/24019382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0681 |
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