The AKT1/NF-kappaB/Notch1/PTEN axis has an important role in chemoresistance of gastric cancer cells

The inherent resistance of tumors to DNA damage often limits the efficacy of chemotherapy. The aim of this work is to explore the potential mechanism for development of chemoresistance in gastric cancer. Our data revealed that AKT1 mRNA and protein expression were induced by doxorubicin (a chemother...

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Detalhes bibliográficos
Main Authors: Zhou, W, Fu, X-Q, Zhang, L-L, Zhang, J, Huang, X, Lu, X-H, Shen, L, Liu, B-N, Liu, J, Luo, H-S, Yu, J-P, Yu, H-G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824684/
https://ncbi.nlm.nih.gov/pubmed/24113181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.375
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