Aurora-A promotes chemoresistance in hepatocelluar carcinoma by targeting NF-kappaB/microRNA-21/PTEN signaling pathway

Hepatocellular carcinoma (HCC) is highly resistant to chemotherapy. Previously, we have shown that Aurora-A mRNA is upregulated in HCC cells or tissues and silencing of Aurora-A using small interfering RNA (siRNA) decreases growth and enhances apoptosis in HCC cells. However, the clinical significan...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Kai, Chen, Jing, Chen, Dongqin, Huang, Jiayuan, Feng, Bing, Han, Siqi, Chen, Yitian, Song, Haizhu, De, Wei, Zhu, Ziman, Wang, Rui, Chen, Longbang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350360/
https://ncbi.nlm.nih.gov/pubmed/25428915
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