Opposing effects of high- and low-molecular weight hyaluronan on CXCL12-induced CXCR4 signaling depend on CD44

The tumor microenvironment makes a decisive contribution to the development and dissemination of cancer, for example, through extracellular matrix components such as hyaluronan (HA), and through chemokines that regulate tumor cell behavior and angiogenesis. Here we report a molecular link between HA...

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Detalhes bibliográficos
Main Authors: Fuchs, K, Hippe, A, Schmaus, A, Homey, B, Sleeman, J P, Orian-Rousseau, V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824673/
https://ncbi.nlm.nih.gov/pubmed/24091662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.364
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