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CD44 mediates the catch-bond activated rolling of HEPG2Iso epithelial cancer cells on hyaluronan

The attachment of cancer cells to the endothelium is an essential step during metastatic dissemination. The cell surface receptor CD44 is capable of binding to hyaluronan (HA) produced by tumor cells and by cells of the tumor microenvironment, including blood endothelial cells. Here, we investigated...

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Bibliografiske detaljer
Udgivet i:Cell Adh Migr
Main Authors: Hanke-Roos, Maximilian, Fuchs, Katharina, Maleschlijski, Stojan, Sleeman, Jonathan, Orian-Rousseau, Véronique, Rosenhahn, Axel
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810759/
https://ncbi.nlm.nih.gov/pubmed/27874296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2016.1260809
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