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Modeling the Synergy of Cofilin and Arp2/3 in Lamellipodial Protrusive Activity
Rapid polymerization of actin filament barbed ends generates protrusive forces at the cell edge, leading to cell migration. Two important regulators of free barbed ends, cofilin and Arp2/3, have been shown to work in synergy (net effect greater than additive). To explore this synergy, we model the d...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3824550/ https://ncbi.nlm.nih.gov/pubmed/24209839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.09.013 |
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