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A Temporal Model of Cofilin Regulation and the Early Peak of Actin Barbed Ends in Invasive Tumor Cells

Cofilin is an important regulator of actin polymerization, cell migration, and chemotaxis. Recent experimental data on mammary carcinoma cells reveal that stimulation by epidermal growth factor (EGF) generates a pool of active cofilin that results in a peak of actin filament barbed ends on the times...

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Detalhes bibliográficos
Main Authors: Tania, Nessy, Prosk, Erin, Condeelis, John, Edelstein-Keshet, Leah
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077689/
https://ncbi.nlm.nih.gov/pubmed/21504724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.02.036
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