Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding

Newly generated actin free barbed ends at the front of motile cells provide sites for actin filament assembly driving membrane protrusion. Growth factors induce a rapid biphasic increase in actin free barbed ends, and we found both phases absent in fibroblasts lacking H(+) efflux by the Na-H exchang...

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Detalhes bibliográficos
Main Authors: Frantz, Christian, Barreiro, Gabriela, Dominguez, Laura, Chen, Xiaoming, Eddy, Robert, Condeelis, John, Kelly, Mark J.S., Jacobson, Matthew P., Barber, Diane L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592832/
https://ncbi.nlm.nih.gov/pubmed/19029335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200804161
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