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Lamellipodium tip actin barbed ends serve as a force sensor

Cells change direction of migration by sensing rigidity of environment and traction force, yet its underlying mechanism is unclear. Here we show that tip actin barbed ends serve as an active ‘force sensor’ at the leading edge. We established a method to visualize intracellular single-molecule fluore...

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書目詳細資料
發表在:Genes Cells
Main Authors: Koseki, Kazuma, Taniguchi, Daisuke, Yamashiro, Sawako, Mizuno, Hiroaki, Vavylonis, Dimitrios, Watanabe, Naoki
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856401/
https://ncbi.nlm.nih.gov/pubmed/31514256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gtc.12720
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