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Lamellipodium tip actin barbed ends serve as a force sensor

Cells change direction of migration by sensing rigidity of environment and traction force, yet its underlying mechanism is unclear. Here we show that tip actin barbed ends serve as an active ‘force sensor’ at the leading edge. We established a method to visualize intracellular single-molecule fluore...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Genes Cells
Asıl Yazarlar: Koseki, Kazuma, Taniguchi, Daisuke, Yamashiro, Sawako, Mizuno, Hiroaki, Vavylonis, Dimitrios, Watanabe, Naoki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856401/
https://ncbi.nlm.nih.gov/pubmed/31514256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gtc.12720
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