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Lamellipodium tip actin barbed ends serve as a force sensor

Cells change direction of migration by sensing rigidity of environment and traction force, yet its underlying mechanism is unclear. Here we show that tip actin barbed ends serve as an active ‘force sensor’ at the leading edge. We established a method to visualize intracellular single-molecule fluore...

詳細記述

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書誌詳細
出版年:Genes Cells
主要な著者: Koseki, Kazuma, Taniguchi, Daisuke, Yamashiro, Sawako, Mizuno, Hiroaki, Vavylonis, Dimitrios, Watanabe, Naoki
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856401/
https://ncbi.nlm.nih.gov/pubmed/31514256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gtc.12720
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