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Lamellipodium tip actin barbed ends serve as a force sensor
Cells change direction of migration by sensing rigidity of environment and traction force, yet its underlying mechanism is unclear. Here we show that tip actin barbed ends serve as an active ‘force sensor’ at the leading edge. We established a method to visualize intracellular single-molecule fluore...
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| Veröffentlicht in: | Genes Cells |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6856401/ https://ncbi.nlm.nih.gov/pubmed/31514256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gtc.12720 |
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