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Modeling the Synergy of Cofilin and Arp2/3 in Lamellipodial Protrusive Activity

Rapid polymerization of actin filament barbed ends generates protrusive forces at the cell edge, leading to cell migration. Two important regulators of free barbed ends, cofilin and Arp2/3, have been shown to work in synergy (net effect greater than additive). To explore this synergy, we model the d...

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Detalhes bibliográficos
Main Authors: Tania, Nessy, Condeelis, John, Edelstein-Keshet, Leah
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824550/
https://ncbi.nlm.nih.gov/pubmed/24209839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.09.013
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