Coactosin-Like 1 Antagonizes Cofilin to Promote Lamellipodial Protrusion at the Immune Synapse

Actin depolymerizing factor-homology (ADF-H) family proteins regulate actin filament dynamics at multiple cellular locations. Herein, we have investigated the function of the ADF-H family member coactosin-like 1 (COTL1) in the regulation of actin dynamics at the T cell immune synapse (IS). We initia...

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Detalhes bibliográficos
Main Authors: Kim, Joanna, Shapiro, Michael J., Bamidele, Adebowale O., Gurel, Pinar, Thapa, Puspa, Higgs, Henry N., Hedin, Karen E., Shapiro, Virginia S., Billadeau, Daniel D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890291/
https://ncbi.nlm.nih.gov/pubmed/24454796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085090
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