Excitable Actin Dynamics in Lamellipodial Protrusion and Retraction

Many animal cells initiate crawling by protruding lamellipodia, consisting of a dense network of actin filaments, at their leading edge. We imaged XTC cells that exhibit flat lamellipodia on poly-L-lysine-coated coverslips. Using active contours, we tracked the leading edge and measured the total am...

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Bibliografiske detaljer
Main Authors: Ryan, Gillian L., Petroccia, Heather M., Watanabe, Naoki, Vavylonis, Dimitrios
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2012
Fag:
Biological Systems and Multicellular Dynamics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318140/
https://ncbi.nlm.nih.gov/pubmed/22500749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.005
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