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Mechano-Chemical Feedbacks Regulate Actin Mesh Growth in Lamellipodial Protrusions

During cell motion on a substratum, eukaryotic cells project sheetlike lamellipodia which contain a dynamically remodeling three-dimensional actin mesh. A number of regulatory proteins and subtle mechano-chemical couplings determine the lamellipodial protrusion dynamics. To study these processes, we...

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Bibliographic Details
Main Authors: Hu, Longhua, Papoian, Garegin A.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856144/
https://ncbi.nlm.nih.gov/pubmed/20409456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.11.054
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