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Membrane Tension, Myosin Force, and Actin Turnover Maintain Actin Treadmill in the Nerve Growth Cone

A growth cone is a motile structure at the tips of axons that is driven by the actin network and guides axon extension. Low actin adhesion to the substrate creates a stationary actin treadmill that allows leading-edge protrusion when adhesion increases in response to guidance cues. We use experiment...

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Detalhes bibliográficos
Main Authors: Craig, Erin M., Van Goor, David, Forscher, Paul, Mogilner, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318135/
https://ncbi.nlm.nih.gov/pubmed/22500750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.003
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