The AKT Inhibitor MK-2206 is Cytotoxic in Hepatocarcinoma Cells Displaying Hyperphosphorylated AKT-1 and Synergizes with Conventional Chemotherapy

Hepatocellular carcinoma (HCC) is one of the most common potentially lethal human malignancies worldwide. Advanced or recurrent HCC is frequently resistant to conventional chemotherapeutic agents and radiation. Therefore, targeted agents with tolerable toxicity are mandatory to improve HCC therapy a...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Simioni, Carolina, Martelli, Alberto M., Cani, Alice, Cetin-Atalay, Rengul, McCubrey, James A., Capitani, Silvano, Neri, Luca M.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2013
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824526/
https://ncbi.nlm.nih.gov/pubmed/24036604
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires