Papuamine causes autophagy following the reduction of cell survival through mitochondrial damage and JNK activation in MCF-7 human breast cancer cells

We previously reported that extracts of an Indonesian marine sponge Haliclona sp. showed potent cytotoxicity and the induction of apoptosis against human solid cancer cell lines. In this study, we examine the cytotoxic mechanism of the major chemical compound, papuamine, on MCF-7 human breast cancer...

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Hlavní autoři: KANNO, SYU-ICHI, YOMOGIDA, SHIN, TOMIZAWA, AYAKO, YAMAZAKI, HIROYUKI, UKAI, KAZUYO, MANGINDAAN, REMY E.P., NAMIKOSHI, MICHIO, ISHIKAWA, MASAAKI
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823348/
https://ncbi.nlm.nih.gov/pubmed/24026338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2013.2093
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