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Exogenous albumin inhibits sorafenib-induced cytotoxicity in human cancer cell lines
Sorafenib is an orally administered multikinase inhibitor that exhibits anti-angiogenic and anti-tumor activity. Sorafenib is also known to bind to protein (>99.5%), suggesting protein binding may be involved in sorafenib pharmacokinetic variability. Albumin is a major drug-binding protein. In th...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3956243/ https://ncbi.nlm.nih.gov/pubmed/24649118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2012.3 |
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