Src promotes delta opioid receptor (DOR) desensitization by interfering with receptor recycling

An important limitation in the clinical use of opiates is progressive loss of analgesic efficacy over time. Development of analgesic tolerance is tightly linked to receptor desensitization. In the case of delta opioid receptors (DOR), desensitization is especially swift because receptors are rapidly...

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Bibliographic Details
Main Authors: Archer-Lahlou, Elodie, Audet, Nicolas, Amraei, Mohammad Gholi, Huard, Karine, Paquin-Gobeil, Mélanie, Pineyro, Graciela
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2009
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823043/
https://ncbi.nlm.nih.gov/pubmed/18363847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00308.x
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