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Ligand- and cell-dependent determinants of internalization and cAMP modulation by delta opioid receptor (DOR) agonists
Signaling bias refers to G protein-coupled receptor ligand ability to preferentially activate one type of signal over another. Bias to evoke signaling as opposed to sequestration has been proposed as a predictor of opioid ligand potential for generating tolerance. Here we measured whether delta opio...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer Basel
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3952036/ https://ncbi.nlm.nih.gov/pubmed/24022593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1461-7 |
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