Enhanced internalization of ErbB2 in SK-BR-3 cells with multivalent forms of an artificial ligand

Targeting and down-regulation of ErbB2, a member of EGF receptor family, is regarded as one of the key aspect for cancer treatment because it is often overexpressed in breast and ovarian cancer cells. Although natural ligands for ErbB2 have not been found, unlike other ErbB receptors, EC-1, a 20-ami...

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Main Authors: Vaidyanath, Arun, Hashizume, Toshihiro, Nagaoka, Tadahiro, Takeyasu, Nao, Satoh, Hitomi, Chen, Ling, Wang, Jiyou, Kasai, Tomonari, Kudoh, Takayuki, Satoh, Ayano, Fu, Li, Seno, Masaharu
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Publishing Ltd 2011
נושאים:
Original Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822962/
https://ncbi.nlm.nih.gov/pubmed/21323863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01277.x
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