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Egf binding to its receptor triggers a rapid tyrosine phosphorylation of the erbB-2 protein in the mammary tumor cell line SK-BR-3.

The epidermal growth factor receptor (EGF-R) and the erbB-2 proto-oncogene product protein are closely related by their structural homology and their shared enzymatic activity as autophosphorylating tyrosine kinases. We show that in mammary tumor cells (SK-BR-3) EGF causes a rapid increase in tyrosi...

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Bibliografische gegevens
Hoofdauteurs: King, C R, Borrello, I, Bellot, F, Comoglio, P, Schlessinger, J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1988
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC457148/
https://ncbi.nlm.nih.gov/pubmed/2901952
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